动物为什么要睡觉？一直醒着会发生什么？( 八 )_作者：喵奴·Cathy编辑：Ceo、Yuki睡眠

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排版：凝音

题图来源：Unsplash

参考文献：

[1]Zada, D., et al., Sleep increases chromosome dynamics to enable reduction of accumulating DNA damage in single neurons. Nature communications, 2019. 10(1): p. 895-895.

[2]Kalueff, A.V., A.M. Stewart, and R. Gerlai, Zebrafish as an emerging model for studying complex brain disorders. Trends in pharmacological sciences, 2014. 35(2): p. 63-75.

[3]Yokogawa, T., et al., Characterization of sleep in zebrafish and insomnia in hypocretin receptor mutants. PLoS Biol, 2007. 5(10): p. e277.

[4]Suberbielle, E., et al., Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-beta. Nat Neurosci, 2013. 16(5): p. 613-21.

[5]Lieber, M.R., The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu Rev Biochem, 2010. 79: p. 181-211.