膳食补充剂NMN：掉落凡间的“长生不老仙丹”？！( 三 )

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极养视点

NMN是一种维生素B族衍生物，也是NAD+的前体之一，其抗衰老作用通过转化为NAD+实现。有动物实验证明， NMN可提升体内NAD+水平，改善衰老相关指标；
因NMN性质比NAD+更稳定且更易被人体吸收，可以直接为身体提供合成NAD+的原料，所以被作为膳食补充剂的常见形式；
在我国， NMN尚未被批准用于普通食品及保健食品，因此只能购买进口NMN ，价格昂贵且质量不受我国相关部门监管；
目前， NMN只拥有一篇广普性并不太好的人体临床研究，且其并未测量NMN在人体内转化为NAD+的效率。 NMN的安全性与有效性还需要未来更多样本量更大，持续时间更长的人体试验进行证明；
烟酸、色氨酸、烟酰胺及烟酰胺核糖都是NAD+的前体，补充上述物质也很有希望增加体内NAD+的水平。除补充前体物质外，通过锻炼及热量限制等方式提升NAMPT等NAD+合成关键限速酶的表达，也可以达到增加NAD+生物合成的效果。因此，从良好生活方式着手或许能比依赖某一补充剂带来更为全面的效果。

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参考文献
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